MyKidneyDiseaseCenter

No, IgA Nephropathy and Lupus Nephritis are not the same condition. IgA Nephropathy (also called Berger's disease) is specifically caused by IgA antibodies forming clumps in the kidneys' filtering units (glomeruli). These antibodies are meant to fight bacteria and viruses but become abnormal in IgAN patients. In IgA Nephropathy, the immune system specifically has trouble with IgA antibodies, which build up in the kidneys and cause inflammation. The condition occurs when these antibodies get stuck in the kidney's filters, leading to inflammation and potential kidney damage over time.