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IgA Nephropathy (IgAN) is like having overprotective bouncers (IgA antibodies) in your kidneys that get too excited about their job. These antibodies, which normally help fight infections, start building up in your kidney filters (glomeruli). Over time, this buildup can cause inflammation and scarring, making it harder for your kidneys to clean your blood properly.

Think of it like a clogged coffee filter - when the filter gets gunked up, it can't strain the coffee as well. Similarly, when IgA proteins build up in your kidneys, they can't filter your blood as effectively as they should.

It's a chronic condition that typically develops slowly over many years, and symptoms can vary from person to person.